Author

Michela Barbato

Simons Initiative for the Developing BrainORCID 0000-0002-8101-2120Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Danilo NegroiD· 1 shared David Jonathan PriceiD· 1 shared Helen Marshall· 1 shared John O. MasoniD· 1 shared Lusi Zhao· 1 shared Mariana BeltrániD· 1 shared Megan BrowniD· 1 shared Neil Cowan HendersoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Danilo NegroORCID

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1 paper

Recent·Most cited

Loss of PAX6 alters the excitatory/inhibitory neuronal ratio in human cerebral organoids

Wai Kit Chan, Shibla Abdulla, Lusi Zhao, Danilo Negro, Victoria M Munro, Sophie R. Thomson, Helen Marshall, Zrinko Kozić, Megan Brown, Michela Barbato, Mariana Beltrán, Neil Cowan Henderson, David Jonathan Price, John O. Mason

This study shows that PAX6 deficiency in human cerebral organoids leads to an increased inhibitory neuron population and altered excitatory/inhibitory ratio due to dysregulated PTN-PTPRZ1 signaling.

Development · Oct 26, 2026Peer-reviewedDevelopmental Biology