Cell-death induced immune response and coagulopathy promote cachexia in Drosophila
Ankita Singh, Yanhui Hu, Raphael Lopes, Liz Lane, Hilina B. Woldemichael, Charles Xu, Namrata D. Udeshi, Steven A. Carr, Norbert Perrimon
This study identifies coagulation and immune factors secreted by Drosophila gut tumors that contribute to cachexia via NFκB and JNK pathways.
bioRxiv · Jan 7, 2025 · PreprintGenetics