Lindsey A. Schier

This study shows that early exposure to a high-fat diet in mice leads to premature maturation of satiation responses and lasting changes in appetitive behaviors, with sex-specific effects on overconsumption of calorie-dense foods.

The paper identifies an enzymatic-metabolic sensing mechanism in taste cells that detects glucose-yielding carbohydrates independently of sweet taste receptors, showing its role in dietary choice.

This study shows that an AGE-rich diet during adolescence impairs memory via hippocampal synaptic deficits and microbiome changes, which can be mitigated by AGE inhibitors.

This study shows that vagus nerve-mediated acetylcholine release in the dorsal hippocampus supports memory function, and its disruption contributes to obesity-induced cognitive impairments.

This study identifies hypothalamic MCH neurons that integrate food-related appetitive and consummatory processes through physiological and behavioral responses.

This study shows that early-life low-calorie sweetener consumption in rodents leads to long-term metabolic, behavioral, and neural impairments without weight gain.