Author

Londen C. Johnson

University of California, Santa CruzORCID 0000-0002-8196-4957Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 4 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

James Matthew RagleiD· 4 shared Jordan D. WardiD· 4 shared Guinevere E. AshleyiD· 3 shared David Q. MatusiD· 2 shared Hannah N. SaegeriD· 2 shared Joseph L. AguileraiD· 2 shared Max T. LevensoniD· 2 shared Michael A. Q. MartineziD· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersDevelopmental Biology

James Matthew RagleORCID

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4 papers

Recent·Most cited

Molecular BiologyDevelopmentPeer-reviewedMay 2, 2023

NHR-23 activity is necessary for C. elegans developmental progression and apical extracellular matrix structure and function

Londen C. Johnson, An A. Vo, John C. Clancy…·Jordan D. Ward

This paper shows that NHR-23 is essential for C. elegans development and apical extracellular matrix structure by regulating gene expression in seam and hypodermal cells.

35 citations

C. elegansexperimental assay

GeneticsGeneticsPeer-reviewedJan 20, 2021

Expanding the Caenorhabditis elegans auxin-inducible degron system toolkit with internal expression and degradation controls and improved modular constructs for CRISPR/Cas9-mediated genome editing

Guinevere E. Ashley, Tam Duong, Max T. Levenson…·Jordan D. Ward

The paper introduces new tools for the auxin-inducible degron system in C. elegans, enabling conditional protein depletion through CRISPR/Cas9-mediated genome editing.

176 citationstop 1%

C. elegansexperimental assay

Developmental BiologyDevelopmentPeer-reviewedJan 1, 2020

The conserved molting/circadian rhythm regulator NHR-23/NR1F1 serves as an essential co-regulator of C. elegans spermatogenesis

James Matthew Ragle, Abigail L. Aita, Kayleigh N. Morrison…·Jordan D. Ward

This study identifies NHR-23/NR1F1 as a critical regulator of spermatogenesis in C. elegans, functioning downstream of the sex determination pathway and independent of the SPE-44 network.

28 citations

C. elegansexperimental assay

Developmental BiologybioRxivPreprintSep 28, 2019

Rapid degradation of C. elegans proteins at single-cell resolution with a synthetic auxin

Michael A. Q. Martinez, Brian A. Kinney, Taylor N. Medwig-Kinney…·David Q. Matus

This paper improves the AID system in C. elegans for single-cell protein degradation using NAA and demonstrates its application in developmental studies.

DOI 10.1101/716837

C. elegansimaging