Author

Alejandra Freire‐Regatillo

InsermORCID 0000-0002-8202-5871Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

Carla GelleiD· 1 shared Chloé Najdek· 1 shared Devrim KilinciD· 1 shared Dolores Siedlecki‐WullichiD· 1 shared Erwan LambertiD· 1 shared Florie Demiautte· 1 shared Frank LafontiD· 1 shared Jean‐Charles LambertiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Carla GelleORCID

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1 paper

Recent·Most cited

BIN1 expression in the presynaptic compartment leads to isoform-specific synaptotoxicity

Erwan Lambert, Carla Gelle, Valentin Leclerc, Alejandra Freire‐Regatillo, Nicolas Barois, Tommy Malfoi, Xavier Hermant, Florie Demiautte, Frank Lafont, Philippe Amouyel, K. Blary, Sabine Kuenen, Chloé Najdek, Patrik Verstreken, Dolores Siedlecki‐Wullich, , Pierre Dourlen

This study shows that BIN1 isoform 1 expression in the presynaptic compartment causes synaptotoxicity, leading to synaptic loss and structural changes in Drosophila and rat models.

bioRxiv · Aug 11, 2025 · PreprintNeuroscience