Author

Shashank Pant

University of Illinois Urbana-ChampaignORCID 0000-0002-8222-3616Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

Emad TajkhorshidiD· 2 shared Qianyi WuiD· 2 shared Renae M. RyaniD· 2 shared Alastair Garner· 1 shared Ashkan Fakharzadeh· 1 shared Azman AkhteriD· 1 shared Chelsea Briot· 1 shared Donald J. van MeyeliD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Emad TajkhorshidORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintNov 10, 2026

One high-order ion-coupling mechanism generates multiple SLC1A stoichiometries

Renae M Ryan, Qianyi Wu, Yan Jiang…·Emad Tajkhorshid

This study identifies a high-order ion-coupling mechanism in EAAT transporters by showing that dEAAT2 can acquire Na+, H+, and K+ dependence through mutations, mimicking human hEAAT2's complex ion coupling.

DOI 10.64898/2026.11.07.764996

Drosophilaexperimental assay

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NeuroscienceJournal of Clinical InvestigationPeer-reviewedFeb 15, 2022

Ataxia-linked SLC1A3 mutations alter EAAT1 chloride channel activity and glial regulation of CNS function

Qianyi Wu, Azman Akhter, Shashank Pant…·Renae M. Ryan

The paper investigates how mutations in SLC1A3 (hEAAT1) affect chloride channel activity and glutamate transport in glial cells, linking these changes to the pathology of episodic ataxia type 6.

22 citations

humanDrosophila

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