Cancer BiologybioRxivPreprint
BRAF V600 and ErbB inhibitors directly activate GCN2 in an off-target manner to limit cancer cell proliferation
Christopher Ryland Ill, Nasreen C. Marikar, Vu Nguyen…·Sabrina L. Spencer
The paper identifies off-target activation of GCN2 by BRAF and EGFR inhibitors, showing it limits cancer cell proliferation.
5 citations