BiophysicsNature Structural & Molecular BiologyPeer-reviewed
Haspin kinase binds to a nucleosomal DNA supergroove
Chad W. Hicks, Colin R. Gliech, Sanim Rahman…·Cynthia Wolberger
The paper reports cryo-EM structures of Haspin kinase bound to a nucleosome, revealing its unique DNA supergroove binding mechanism for phosphorylating H3T3.