Chiara Di Vona

DYRK1A regulates cancer cell and cancer-associated fibroblast secretomes to foster an immunosuppressive microenvironment in pancreatic cancer

This study shows DYRK1A regulates secretomes in pancreatic cancer cells and CAFs, promoting immunosuppressive signaling in the tumor microenvironment.

THE DUAL-SPECIFICITY KINASE DYRK1A INTERACTS WITH THE HEPATITIS B VIRUS GENOME AND REGULATES THE PRODUCTION OF VIRAL RNA

This study identifies DYRK1A as a kinase that interacts with HBV cccDNA and enhances HBV RNA production by regulating the enhancer 1/X promoter.

Loss of the DYRK1A protein kinase results in reduction of ribosomal protein genes expression, ribosome mass and translation defects

This study shows that DYRK1A regulates ribosomal protein gene expression, ribosome mass, and translation in mammals by interacting with promoters and affecting transcription factor binding.

TFIIIC binding to Alu elements controls gene expression via chromatin looping and histone acetylation

The paper shows TFIIIC binding to Alu elements regulates gene expression through chromatin looping and histone acetylation during serum starvation.