Susana de la Luna

This study shows DYRK1A regulates secretomes in pancreatic cancer cells and CAFs, promoting immunosuppressive signaling in the tumor microenvironment.

This study identifies DYRK1A as a kinase that interacts with HBV cccDNA and enhances HBV RNA production by regulating the enhancer 1/X promoter.

This study shows that DYRK1A regulates ribosomal protein gene expression, ribosome mass, and translation in mammals by interacting with promoters and affecting transcription factor binding.

The paper shows TFIIIC binding to Alu elements regulates gene expression through chromatin looping and histone acetylation during serum starvation.

This study shows that DYRK1A haploinsufficiency leads to impaired neocortical circuit development, contributing to neurological symptoms in a syndrome related to Down syndrome.

The paper investigates the role of amino acid repeat expansions in the functional diversification of duplicated transcription factors following whole genome duplications.