Author

Alexandra M. Hoyt-Miggelbrink

Duke UniversityORCID 0000-0003-1499-2269Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Katayoun AyasoufiiD· 2 shared Kelly M. HotchkissiD· 2 shared Aaron J. JohnsoniD· 1 shared Aditya A MohaniD· 1 shared Andrew A. HardiganiD· 1 shared Anoop P. PateliD· 1 shared Christian Karl PfalleriD· 1 shared Cori E. FainiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Katayoun AyasoufiORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 26, 2025

Antigen-specific CD8 T cells are generated and reactivated in the bone marrow following viral brain infections and impact the bone marrow niche

Delaney M. Wolf, Kelly M. Hotchkiss, Rachael Ann Reesman…·Katayoun Ayasoufi

This study shows that virus-specific CD8 T cells are generated and reactivated in the bone marrow after brain viral infections, leading to changes in the bone marrow niche.

1 citation

mouseflow cytometry

𝕏 PostBluesky

ImmunologyClinical Cancer ResearchPeer-reviewedNov 21, 2025

Upregulation of TNFR2 Precedes TOX Expression by Exhausted T cells and Restricts Antitumor and Antiviral Immunity

Alexandra M. Hoyt-Miggelbrink, Jessica Waibl Polania, Lucas P. Wachsmuth…·Peter Edward Fecci

6 citations

mousebulk RNA-seq

𝕏 PostBluesky