Daniel Flickinger

This paper introduces SLAP2, a high-speed microscope for measuring submicron synapses and dendritic voltage in behaving mice, revealing nonlinear input-output amplification in neurons.

This paper introduces a new system for activating and recording thousands of neurons over a large field-of-view with pixel-level precision.

The paper investigates whether perceptual learning in mice is due to supervised or unsupervised learning by analyzing neural activity in visual cortex during task learning and unrewarded exposure.

The paper shows that learning in the hippocampus produces orthogonalized neural representations resembling a state machine, captured by HMMs and biologically plausible networks, but not by gradient-based models.

The paper introduces a high-throughput instrument called GIZMO to screen fluorescent protein mutants under two-photon excitation, enabling efficient evolution of proteins optimized for this excitation method.

This study uses calcium imaging in mouse motor cortex pyramidal cells to show that dendritic activity during decision-making is compartmentalized by branching and clustered within branches.

This paper introduces a two-photon imaging technique that achieves high-speed, high-resolution imaging of neural activity in mice at over 1 kHz frame rates.

This paper introduces a 2-photon mesoscope with subcellular resolution for in vivo imaging across multiple brain areas in mice.