Rosana S. Molina

This paper introduces a streamlined platform for luciferase engineering using continuous hypermutation, resulting in improved light output variants without manual library generation.

This paper introduces two new far-red fluorescent GECIs, FR-GECO1a and FR-GECO1c, characterized for their Ca2+ sensitivity and performance in neuronal imaging.

This paper develops a genetically encoded fluorescent biosensor for extracellular L-lactate and demonstrates its use in imaging in cultured mammalian cells and brain tissue.

This paper develops a hybrid chemical-genetic voltage reporter for voltage imaging in Drosophila, enabling selective neuron labeling and voltage monitoring in intact tissues.

The paper introduces a high-throughput instrument called GIZMO to screen fluorescent protein mutants under two-photon excitation, enabling efficient evolution of proteins optimized for this excitation method.