Author

Sarah Delaney

Brown UniversityORCID 0000-0002-8366-3808Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Abigayle F. VitoiD· 1 shared Bret FreudenthaliD· 1 shared Caleb S JacquesiD· 1 shared Carlos H. Trasviña‐ArenasiD· 1 shared Emmanuelle BignoniD· 1 shared Julia C. FerraraiD· 1 shared Justin A. LingiD· 1 shared Mohammad Hashemian· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Abigayle F. VitoORCID

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1 paper

Recent·Most cited

Structure, dynamics, and processing of 8oxoG:A in the nucleosome

Abigayle F. Vito, Justin A. Ling, Julia C. Ferrara, Caleb S Jacques, Natacha Gillet, Roy González‐Alemán, Yuya Qiu, Mohammad Hashemian, Carlos H. Trasviña‐Arenas, Sheila S. David, Sarah Delaney, Emmanuelle Bignon, Bret Freudenthal

This study determines the structure and dynamics of 8oxoG:C and 8oxoG:A base pairs in the nucleosome and characterizes MUTYH activity, revealing that 8oxoG:A is less processable by MUTYH.

bioRxiv · Sep 2, 2025 · PreprintBiochemistry