Author

Alexys R. Berman

University of UtahORCID 0000-0002-8377-7426Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:Drosophila· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2

Frequent Co-Authors

Clement Y. ChowiD· 2 shared Hans M. DaltoniD· 2 shared Heather D Evans· 1 shared Jae Sophia Zuno· 1 shared Kaylee A Patterson· 1 shared Naomi J. Young· 1 shared Norbert PerrimoniD· 1 shared Raghuvir ViswanathaiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetics

Clement Y. ChowORCID

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2 papers

Recent·Most cited

A drug repurposing screen reveals dopamine signaling as a critical pathway underlying potential therapeutics for the rare disease DPAGT1-CDG

Hans M. Dalton, Naomi J. Young, Alexys R. Berman, Heather D Evans, Sydney J Peterson, Kaylee A Patterson, Clement Y. Chow

A drug repurposing screen in a Drosophila model of DPAGT1-CDG identified dopamine D2 receptor inhibition as a potential therapeutic strategy.

PLoS Genetics · Oct 28, 2024Peer-reviewedGenetics

A genome-wide CRISPR screen identifies the glycosylation enzyme DPM1 as a modifier of DPAGT1 deficiency and ER stress

Hans M. Dalton, Raghuvir Viswanatha, Roderick Brathwaite, Jae Sophia Zuno, Alexys R. Berman, Rebekah Rushforth, Stephanie Elizabeth Mohr, Norbert Perrimon, Clement Y. Chow

The paper identifies DPM1 as a therapeutic target for DPAGT1-CDG by showing its inhibition rescues ER stress and glycoprotein levels in Drosophila models.

PLoS Genetics · Sep 27, 2022Peer-reviewedGenetics