Author

Hans M. Dalton

University of UtahORCID 0000-0001-7916-1015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:Drosophila· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Clement Y. ChowiD· 4 shared Alexys R. BermaniD· 2 shared Naomi J. Young· 2 shared Elizabeth M. BrydoniD· 1 shared Heather D Evans· 1 shared Jae Sophia Zuno· 1 shared Katie G OwingsiD· 1 shared Kaylee A Patterson· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenetics

Clement Y. ChowORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The stress-induced transcription factor ATF4 has multiple conserved retrocopies that can alter gene expression

Hans M. Dalton, Elizabeth M. Brydon, Tiffany S. Chan, Katie G Owings, Mandi ML Wild, Naomi J. Young, Clement Y. Chow

This study identifies and characterizes conserved ATF4 retrocopies in primates that are functionally active and influence ISR signaling.

Human Genetics and Genomics Advances · Aug 27, 2026Peer-reviewedGenetics

A drug repurposing screen reveals dopamine signaling as a critical pathway underlying potential therapeutics for the rare disease DPAGT1-CDG

Hans M. Dalton, Naomi J. Young, Alexys R. Berman, Heather D Evans, Sydney J Peterson, Kaylee A Patterson, Clement Y. Chow

A drug repurposing screen in a Drosophila model of DPAGT1-CDG identified dopamine D2 receptor inhibition as a potential therapeutic strategy.

PLoS Genetics · Oct 28, 2024Peer-reviewedGenetics

A genome-wide CRISPR screen identifies the glycosylation enzyme DPM1 as a modifier of DPAGT1 deficiency and ER stress

Hans M. Dalton, Raghuvir Viswanatha, Roderick Brathwaite, Jae Sophia Zuno, Alexys R. Berman, Rebekah Rushforth, Stephanie Elizabeth Mohr, Norbert Perrimon, Clement Y. Chow

The paper identifies DPM1 as a therapeutic target for DPAGT1-CDG by showing its inhibition rescues ER stress and glycoprotein levels in Drosophila models.

PLoS Genetics · Sep 27, 2022Peer-reviewedGenetics

The Drosophila metallopeptidase superdeath decouples apoptosis from the activation of the ER stress response

Rebecca A.S. Palu, Hans M. Dalton, Clement Y. Chow

This study identifies superdeath, a Drosophila metallopeptidase, as a modifier of ER stress-induced apoptosis by acting upstream of CDK5 in the JNK pathway, without affecting the unfolded protein response.

Genetics · Feb 11, 2020Peer-reviewedGenetics