Author

Brian Keith Law

University of FloridaORCID 0000-0002-8411-6531Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Abhisheak SharmaiD· 2 shared Olga A. GuryanovaiD· 2 shared Abhishek GouriD· 1 shared Amandeep Singh· 1 shared Arun Kumar SharmaiD· 1 shared Bianca ForsythiD· 1 shared Boaz TiroshiD· 1 shared Bowen YaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Abhisheak SharmaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyMolecular Cancer TherapeuticsPeer-reviewedApr 17, 2026

CerS2 is a druggable target in triple-negative breast cancer

Hissah Alatawi, Nair Hariprasad Haritha, Lingbao Ai…·Satya Narayan

This paper identifies DH20931 as a first-in-class agonist of CerS2 that induces ER stress and apoptosis in TNBC cells, showing preclinical efficacy.

1 citation

humanproteomics

𝕏 PostBluesky

Cancer BiologyMolecular Cancer ResearchPeer-reviewedMar 19, 2025

DR5 disulfide bonding as a sensor and effector of protein folding stress

Mary E. Law, Zaafir M. Dulloo, Samantha R. Eggleston…·Brian Keith Law

This study shows that disrupting DR5 disulfide bonds activates pro-apoptotic signaling and reveals DR5 disulfide bonding as a sensor and effector of ER stress in cancer cells.

6 citations

humanprotein structure

𝕏 PostBluesky