Author

Arun Kumar Sharma

Pennsylvania State UniversityORCID 0000-0002-7679-7779Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Abhisheak SharmaiD· 1 shared Abhishek GouriD· 1 shared Amandeep Singh· 1 shared Amandeep SinghiD· 1 shared Bowen YaniD· 1 shared Brian Keith LawiD· 1 shared Chandra Kumar MaharjaniD· 1 shared Chris D. VulpeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Abhisheak SharmaORCID

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2 papers

Recent·Most cited

CerS2 is a druggable target in triple-negative breast cancer

Hissah Alatawi, Nair Hariprasad Haritha, Lingbao Ai, Iqbal Mahmud, Abhishek Gour, Amandeep Singh, Doohyun Baek, Bowen Yan, Chandra Kumar Maharjan, Weizhou Zhang, Brian Keith Law, Maria Zajac‐Kaye, Chris D. Vulpe, Olga A. Guryanova, Arun Kumar Sharma, , Satya Narayan

This paper identifies DH20931 as a first-in-class agonist of CerS2 that induces ER stress and apoptosis in TNBC cells, showing preclinical efficacy.

Molecular Cancer Therapeutics · Apr 17, 2026Peer-reviewedCancer Biology

AVJ16 inhibits the RNA binding protein IGF2BP1 in lung adenocarcinomas and prevents tumor growth in mice

Nadav Wallis, Tehila Gershon, Sojod Shaaby, Froma Oberman, Myriam Grunewald, Deborah Duran, Amandeep Singh, Gilad Wolf Vainer, Vladimir S. Spiegelman, Arun Kumar Sharma, Joel K. Yisraeli

AVJ16 inhibits IGF2BP1 in lung adenocarcinoma cells and xenografts, reducing proliferation, enhancing apoptosis, and preventing tumor growth.

Oncogene · Jul 8, 2025Peer-reviewedCancer Biology