Author

Simon Blachier

Centre National de la Recherche ScientifiqueORCID 0000-0002-8438-5555Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Marion RusseauiD· 2 shared Sabine LéviiD· 2 shared Adrien Bouchet· 1 shared Alix BoucharlatiD· 1 shared Anne BrelotiD· 1 shared Célia Delhaye· 1 shared Christophe Piesse· 1 shared Delphine PlanasiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Marion RusseauORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 9, 2025

NKCC1 as a signaling hub regulating KCC2 stability, chloride homeostasis, and seizure susceptibility

Erwan Pol, Célia Delhaye, Silvia Cases‐Cunillera…·Sabine Lévi

The paper identifies NKCC1 as a signaling hub that regulates KCC2 stability and chloride homeostasis, showing that peptides targeting NKCC1 can reduce seizure frequency in epilepsy.

DOI 10.64898/2025.12.05.692569

mousehuman

𝕏 PostBluesky

MicrobiologybioRxivPreprintOct 11, 2024

Intranasal delivery of a broadly neutralizing single domain antibody targeting ACE2 protects against SARS-CoV-2 infection

Simon Blachier, Ignacio Fernández, Laurine Conquet…·Anne Brelot

This paper develops a single domain antibody targeting ACE2 that protects against SARS-CoV-2 infection in mice when delivered intranasally.

DOI 10.1101/2024.10.11.617877

mousehuman

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 11, 2022

Lateral diffusion of NKCC1 contributes to neuronal chloride homeostasis and is rapidly regulated by the WNK signaling pathway

Etienne Côme, Simon Blachier, Juliette Gouhier…·Sabine Lévi

The paper shows that NKCC1 lateral diffusion is regulated by the WNK1-SPAK pathway, affecting chloride homeostasis in neurons.

1 citation

mouseexperimental assay

𝕏 PostBluesky