Ignacio Fernández

This study shows human coronavirus HKU1 replicates more efficiently at nasal temperature (33°C) than at body temperature (37°C), with differences in innate immune response and viral stability.

This study identifies dipeptidase 1 as the receptor for PHEV, showing it does not require sialic acid and reveals structural versatility in receptor binding.

This study uses single-molecule techniques to show that SARS-CoV-2 spike protein RBD dynamics modulate ACE2 binding through conformational selection without affecting unbinding.

This paper investigates how VP3 protein of birnaviruses targets endosomal membranes via PI3P binding, revealing a two-stage mechanism critical for viral replication.

This paper develops a single domain antibody targeting ACE2 that protects against SARS-CoV-2 infection in mice when delivered intranasally.

The paper reports cryo-EM structures of foamy virus Env in pre- and post-fusion states, revealing structural similarity to paramyxovirus F proteins and suggesting an evolutionary link.