Author

Craig M. Crews

Yale UniversityORCID 0000-0002-8456-2005Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Jiasheng ZhangiD· 1 shared Junmin PengiD· 1 shared Kazuhiro IwaïiD· 1 shared Kyrillos AbdallahiD· 1 shared Lawrence H. YoungiD· 1 shared Meghan G. McReynoldsiD· 1 shared Pengju Nie· 1 shared Todd DouglasiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Jiasheng ZhangORCID

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1 paper

Recent·Most cited

An atypical E3 ligase safeguards the ribosome during nutrient stress

Todd Douglas, Pengju Nie, Jiasheng Zhang, Kyrillos Abdallah, Zhiping Wu, Meghan G. McReynolds, Kazuhiro Iwaï, Junmin Peng, Wendy V. Gilbert, Lawrence H. Young, Craig M. Crews

This study identifies HOIL-1 as an atypical E3 ligase that protects the ribosome during nutrient stress, revealing a new signaling pathway involved in cell fate decisions.

Nature Cell Biology · Apr 30, 2026Peer-reviewedCell Biology