Michael Didriksen

Increased Prevalence of Rare Copy Number Variants in Treatment-Resistant Psychosis

The paper finds that rare copy number variants (CNVs) are more common in treatment-resistant psychosis patients compared to a general schizophrenia cohort, with duplications at 15q11.2-q13.1 and 16p11.2 linked to treatment resistance.

Transcriptomic networks implicate neuronal energetic abnormalities in three mouse models harboring autism and schizophrenia-associated mutations

The paper identifies shared gene expression modules in mouse models of autism and schizophrenia that link to neuronal energetic dysfunction.

Individuals with 22q11.2 deletion syndrome show intact prediction but reduced adaptation in responses to repeated sounds: evidence from Bayesian mapping

This study examines neural responses to repeated sounds in individuals with 22q11.2 deletion syndrome, finding reduced adaptation but intact prediction, linked to negative symptom severity.

The neurobiology of BRD1 implicates sex-biased dysregulation of nuclear receptor signaling in mental disorders

This study investigates the role of BRD1 in sex-biased nuclear receptor signaling and its implications in mental disorders using mouse models and gene expression analysis.