Peptide-antibody Fusions Engineered by Phage Display Exhibit Ultrapotent and Broad Neutralization of SARS-CoV-2 Variants
Jonathan M. Labriola, Shane Miersch, Gang Chen, Chao Chen, Alevtina Pavlenco, Reza Saberianfar, Francesca Caccuri, Alberto Zani, Nitin Sharma, Annie Feng, Daisy W. Leung, Arnaldo Caruso, Giuseppe Novelli, Gaya K. Amarasinghe, Sachdev S. Sidhu
This paper describes the engineering of peptide-antibody fusions using phage display to enhance neutralization potency and breadth against SARS-CoV-2 variants.
ACS Chemical Biology · Jun 22, 2022Peer-reviewedSynthetic Biology