Jianxu Chen

BaSiCPy improves illumination correction in microscopy images by addressing foreground correlations and enabling automated processing.

The paper introduces Mask Interpreter, a method to improve interpretability of image-to-image translation models, validating biological relevance and identifying artifacts in in silico labeling.

The paper introduces cellmig, a Bayesian tool for quantifying cell migration velocity with uncertainty, improving reproducibility and biological insight in high-throughput assays.

SIMO integrates spatial metabolomics, lipidomics, and proteomics from a single tissue section to enable comprehensive multi-omics analysis across spatial regions.

The paper analyzes nuclear growth variations in hiPS cell colonies, finding context-dependent and inherited mechanisms shaping growth trajectories.

This paper introduces a 'Bag-of-Experts' model for label-free prediction of multiple organelles across transmitted-light microscopy images, showing generalizability across imaging conditions.

VesselExpress automates 3D blood vasculature analysis in LSFM data, enabling rapid and unbiased quantification of vascular parameters across multiple organs.

This study investigates the in vivo role of intercellular calcium signaling in Drosophila wing development, showing its impact on wing morphology and patterning through chemical stimuli and extracellular matrix interactions.

The paper develops a neural-network-based method to analyze intercellular calcium oscillations in Drosophila wing discs and shows that Hedgehog morphogen controls their frequency and spatial patterning.