Author

Tulio Alberto Valdez

Stanford MedicineORCID 0000-0002-8520-7910Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Emily C. WoodsiD· 2 shared Jeyun JoiD· 2 shared Ki Wan ParkiD· 2 shared Matthew S. BogyoiD· 2 shared Tulsi UpadhyayiD· 2 shared Alexander BarteltiD· 1 shared Alix I ChaniD· 1 shared Althea Hansel-HarrisiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

Emily C. WoodsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Imaging of Staphylococcus aureus infections and biofilms using a selective covalent probe for the unique serine hydrolase FphE

Emily C. Woods, Tulsi Upadhyay, Ki Wan Park, Shih-Po Su, Zhen Xiao, Jianghong Rao, Tulio Alberto Valdez, Jeyun Jo, Matthew S. Bogyo

This study develops a covalent probe for imaging S. aureus biofilms in vitro and in vivo, showing high specificity for the serine hydrolase FphE.

Angewandte Chemie · Apr 30, 2026Peer-reviewedMicrobiology

An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor

Sijie Wang, Emily C. Woods, Jeyun Jo, Jiyun Zhu, Althea Hansel-Harris, Matthew Holcomb, Manuel A. Llanos, Nichole J. Pedowitz, Tulsi Upadhyay, John M. Bennett, Matthias Fellner, Ki Wan Park, Anna Zhang, Tulio Alberto Valdez, Stefano Forli, , Matthew S. Bogyo

The paper develops fluorescent probes for FphB, a Staphylococcus aureus enzyme, using mRNA display with a genetically encoded electrophile, achieving nanomolar selectivity.

Journal of the American Chemical Society · Feb 27, 2025Peer-reviewedMicrobiology

Macroscopic label-free biomedical imaging withshortwave infrared Raman scattering

Bernardo Assein Arús, Joycelyn Yiu, Jakob G. P. Lingg, Anja Hofmann, Amy Rose Fumo, Honglei Ji, Carolin Jethwa, Roy K. Park, James Henderson, Kanuj Mishra, Iuliia Mukha, André C. Stiel, Donato Santovito, Christian Weber, Christian Reeps, , Oliver T. Bruns†

This paper introduces a shortwave infrared Raman imaging technique that enables label-free, high-contrast visualization of tissue composition and pathology without contrast agents.

bioRxiv · Jun 10, 2024 · PreprintBioengineering

Tulio Alberto Valdez · henhao