Jianghong Rao

Imaging of Staphylococcus aureus infections and biofilms using a selective covalent probe for the unique serine hydrolase FphE

This study develops a covalent probe for imaging S. aureus biofilms in vitro and in vivo, showing high specificity for the serine hydrolase FphE.

Endothelial Cu Uptake Transporter CTR1 Senses Disturbed Flow to Promote Atherosclerosis through Cuproptosis

This study shows that endothelial CTR1 senses disturbed flow by increasing mitochondrial copper, leading to cuproptosis and atherosclerosis, and identifies a therapeutic target.

In vivo imaging of T-cell coregulator B7-H4 reveals protumor macrophage status in prostate cancer

This paper develops an immunoPET tracer to visualize B7-H4 in prostate cancer models, showing its ability to detect tumor-associated B7-H4 and macrophage status.