Egil Lien

This paper identifies curli amyloid as a novel activator of the non-canonical inflammasome in dendritic cells, driving hyperactivation without pyroptosis.

This study shows that loss of C3 and CD14 reduces neuroinflammation in a murine polytrauma model, with differential effects across brain regions.

This study identifies Raver1 as a regulator of Ripk1 RNA splicing, which affects caspase-8-mediated pyroptosis, inflammation, and resistance to Yersinia infection.