Author

Jesse W. Lehman

University of Massachusetts Chan Medical SchoolORCID 0000-0002-3729-2866Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:long-read sequencing· 1 Organism:mouse· 1

Frequent Co-Authors

Athma A. PaiiD· 2 shared Alexandre DinisiD· 1 shared Barbara Elizabeth EngelhardtiD· 1 shared Boyao ZhangiD· 1 shared Edric TamiD· 1 shared Egil LieniD· 1 shared Ezequiel Calvo-RoitbergiD· 1 shared John BertiniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Athma A. PaiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

SPARK: in silico simulations for benchmarking nascent RNA sequencing experiments

Ezequiel Calvo-Roitberg, Jesse W. Lehman, Edric Tam, Shaimae I. Elhajjajy, Barbara Elizabeth Engelhardt, Athma A. Pai

SPARK generates simulated nascent RNA sequencing data to benchmark computational tools for analyzing transcriptional dynamics.

bioRxiv · Nov 6, 2025 · PreprintGenomics

Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance

Boyao Zhang, Pontus Ørning, Jesse W. Lehman, Alexandre Dinis, Leslie Torres-Ulloa, Roland Elling, Michelle A. Kelliher, John Bertin, Megan K. Proulx, Jon D. Goguen, Liv Ryan, Richard K. Kandasamy, Terje Espevik, Athma A. Pai, Katherine A. Fitzgerald, Egil Lien

This study identifies Raver1 as a regulator of Ripk1 RNA splicing, which affects caspase-8-mediated pyroptosis, inflammation, and resistance to Yersinia infection.

Proceedings of the National Academy of Sciences · Feb 13, 2025Peer-reviewedImmunology