Rita R. Fagan

The paper shows that primary cilia in striatal neurons facilitate dopamine receptor-initiated cAMP/PKA signaling beyond the cilium, challenging the view that ciliary neurotransmission is restricted to non-canonical pathways.

This study identifies ANIDRA as a Drosophila amino acid transporter that regulates sleep by modulating mTOR activity in glia and affecting arousal-promoting neurons.

The paper shows that endocytosis differentiates cAMP signaling profiles of co-expressed GPCRs by shaping spatiotemporal cAMP dynamics.

This study shows that Rit2 loss in dopamine neurons causes PD-like symptoms in mice, with sex-specific differences in disease progression and response to treatment.

This study investigates the role of Ric GTPase in dopamine transporter function and behavior in Drosophila, finding that RicQ117L affects DAT trafficking and amphetamine sensitivity in a DAT-dependent manner.

This study shows that Hedgehog signaling regulates neurogenesis in the larval and adult zebrafish hypothalamus by promoting proliferation of neural precursors and maintaining a heterogeneous signaling environment.

This study investigates the role of Rit2 GTPase in PKC-stimulated dopamine transporter (DAT) endocytosis in DAergic terminals, revealing region- and sex-specific differences.