Author
University of MinnesotaORCID 0000-0001-6363-2644Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Dain R. Brademan, Angelina A. Mullarkey, Mia L. Greeson…·Ruth Hüttenhain
This paper optimizes and benchmarks synchro-PASEF for phosphoproteomics, showing improved identification and quantification with retention time summation, and comparable performance to dia-PASEF in modeling phosphosignaling.
Brian Wysolmerski, Nicole M. Fisher, Andrew N. Dates…·Mark von Zastrow
This study investigates how GPCRs regulate G protein activity on endosomes using conformational biosensors, finding that endocytosis is required for active Gs production on endosomes.
Emily E. Blythe, Rita R. Fagan, Mark von Zastrow
The paper shows that endocytosis differentiates cAMP signaling profiles of co-expressed GPCRs by shaping spatiotemporal cAMP dynamics.
Benjamin J. Polacco, Braden T. Lobingier, Emily E. Blythe…·Ruth Hüttenhain
The paper identifies novel regulators of mu opioid receptor signaling and trafficking using proximity labeling and proteomics.