Sanjai Patel

GSK-3β coordinates axonal microtubule organisation through Shot and Tau

This study shows that GSK-3β regulates axonal microtubule organisation via Shot and Tau, and misregulation causes microtubule disorganisation linked to neurodegeneration.

How the Drosophila Cryptochrome C-terminus mediates magnetosensitivity

This study identifies FAD binding by the C-terminus of Drosophila CRY as essential for magnetosensitivity, explaining non-canonical magnetosensitivity observations.

Genetic Risk of Axonal Neuropathy Following Infection

The paper identifies biallelic RCC1 variants causing an acute axonal neuropathy triggered by infection, with mechanistic overlap with ALS and GBS.

Activation loop phosphorylation of Cdk11 is restrained by PNUTS-PP1 and regulates Cdk11 activity and function

This study identifies PNUTS-PP1 as a regulator of Cdk11 phosphorylation, showing that dephosphorylation by PNUTS-PP1 modulates Cdk11 activity and affects mRNA processing and splicing.

Ongoing transposition in cell culture reveals the phylogeny of diverse Drosophila S2 sub-lines.

The paper sequenced 25 Drosophila S2 cell sub-lines to show ongoing transposition and use TE insertions for phylogenetic reconstruction in cell culture.