Antonio De Marco

This study shows that protein-coding gene expression can be reliably estimated from small RNA-seq data, comparable to total RNA-seq, and applies this to breast cancer datasets without total RNA-seq.

This study shows LIMD1 is essential for effective miRNA targeting and repression by AGO2, revealing its role in expanding miRNA regulatory capacity beyond conserved targets.

This study examines somatic evolution of cancer genes on sex chromosomes, finding sex-specific differences in mutation rates and inactivation patterns of tumor suppressor and oncogenes.

This study shows RSK2 and RSK4 promote prostate cancer proliferation through distinct mechanisms, both dependent and independent of androgen signaling.

PopTargs compiles and integrates microRNA target site data from multiple sources to enable population-level evolutionary genetic analysis.

SeedVicious predicts microRNA target and near-target sites, detects functional variation, and complements existing tools with improved precision.