FACT frees Ubp10 from nucleosome sequestration after rapid H2B deubiquitination
Raquel Merino-Urteaga, Jonas Zaehringer, Melesse Nune, Cynthia Wolberger, Taekjip Ha
The paper shows that FACT facilitates Ubp10 release from nucleosomes after H2B deubiquitination, revealing release as the rate-limiting step for Ubp10 turnover.
bioRxiv · Nov 9, 2026 · PreprintBiophysics