Andreas R. Bausch

Topological Excitations govern Ordering Kinetics in Endothelial Cell Layers

The paper shows that topological defects and strings mediate ordering in endothelial cell layers, revealing an intermediate phase in their transition from disordered to ordered states.

Phase separation determines treadmilling-like movement ofactin bundles

This paper reconstitutes a minimal in vitro system showing phase-separated condensates enable treadmilling-like movement of actin bundles by balancing cofilin-driven disassembly.

Flow-Induced Vascular Remodeling On-Chip: Implications for Anti-VEGF Therapy

This study uses a human vasculature-on-chip system to show how flow and VEGF levels affect vascular remodeling and response to anti-VEGF therapy.

Effective recognition of double-stranded RNA does not require activation of cellular inflammation

The paper shows that effective dsRNA recognition can occur without inflammation, with distinct pathways activated by different RNA features.

Cluster Formation and Phase Separation Driven by Mobile Myosin Motors in the Motility Assay

This study simulates the motility assay with mobile myosin motors and shows that F-actin clusters form with polar ordering and phase separation, dependent on actin length and concentration.

Accelerated maturation of branched organoids confined in collagen droplets

This study shows that pancreatic ductal adenocarcinoma cells in collagen droplets form branched organoids with complex morphology, suggesting accelerated maturation compared to traditional bulk culture.

Morphodynamic Atlas for Drosophila Development

The paper constructs a morphodynamic atlas integrating fixed and live datasets to study tissue dynamics and gene expression during Drosophila development.

Mechanical plasticity of the ECM directs invasive branching morphogenesis in human mammary gland organoids

This study shows that mechanical feedback from collagen reorganization drives invasive branching in human mammary organoids.