Yongfeng Liu

This paper introduces TUCL-Seq, a single molecule sequencing workflow for miRNA that reduces sample-to-result time and manual interventions, demonstrating its effectiveness with synthetic miRNA samples.

The paper characterizes two MOR PAMs that enhance opioid antinociception without increasing adverse effects in mouse models.

The paper reports the structures of D1R-Gs complex bound to dopamine and LY3154207, revealing mechanisms of dopamine recognition and allosteric modulation for drug discovery.

Affinity-purification mass spectrometry of 26 SARS-CoV-2 proteins in HEK293T cells yields 332 high-confidence host interactions and 67 druggable human proteins with known compounds.