Author

Li Luo

Johns Hopkins UniversityORCID 0000-0002-8680-4119Unclaimed ORCID profile · follow to get notified of new preprints

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Li Luo2 papers · Southern University of Science and Technology

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Linda M S ResariD· 2 shared Amy Elizabeth DezerniD· 1 shared Bin GaoiD· 1 shared Bogdan C. Paun· 1 shared Brandy N. Perkins· 1 shared Bum Seok LeeiD· 1 shared Evangeline Watson· 1 shared Fan YangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Linda M S ResarORCID

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2 papers

Recent·Most cited

Chronic alcohol exposure drives inflammaging and transposon derepression in hematopoietic stem and progenitor cells

Ridzky Anis Advent Yuda, Habin Bea, Valerie Kellett, Jung-Woo Kim, Fan Yang, Haruna B. Choijilsuren, Yejie Park, Yaojie Fu, Zewen Ha, Juhye Choi, Li Luo, Zhaoli Sun, Bin Gao, Sangmoo Jeong, Linda M S Resar, Moonjung Jung

This study shows chronic alcohol exposure leads to inflammation, DNA damage, and transposon activation in hematopoietic stem and progenitor cells, with lasting effects on myeloid bias and immune responses.

bioRxiv · May 8, 2026 · PreprintImmunology

A PBD-dimer containing antibody drug conjugate targeting CCRL2 for high-risk MDS/AML

Nour Sabiha Naji, Taha S. Ahmedna, J. David Peske, Xinghan Zeng, Brandy N. Perkins, Zanshé Thompson, Tushar D. Nichakawade, Bum Seok Lee, Evangeline Watson, Theodora Chatzilygeroudi, Li Luo, Bogdan C. Paun, Melanie Klausner, Yuju An, Teodora Supeanu, , Theodoros Karantanos

This paper develops an anti-CCRL2 antibody-drug conjugate (ADC) that shows potent cytotoxicity against high-risk MDS/AML cells without harming healthy hematopoietic cells.

bioRxiv · Aug 17, 2025 · PreprintCancer Biology