Zhaoli Sun

ExPert infers causal perturbations from cell states across biological and clinical contexts

ExPert infers causal perturbations from cell states by learning prototypes across 12 contexts, achieving high recall with low compute and validating findings in disease models.

Proteomic Identification of Pig Xenoantigens for Clinical Xenotransplantation

This study identifies pig xenoantigens reactive to human preformed antibodies using proteomic and glycoproteomic methods, revealing potential targets for improving xenotransplantation.

Chronic alcohol exposure drives inflammaging and transposon derepression in hematopoietic stem and progenitor cells

This study shows chronic alcohol exposure leads to inflammation, DNA damage, and transposon activation in hematopoietic stem and progenitor cells, with lasting effects on myeloid bias and immune responses.

Dysregulated RNA splicing induces regeneration failure in alcohol-associated liver disease

The paper identifies dysregulated RNA splicing in alcohol-associated liver disease as a cause of regeneration failure, highlighting ESRP2 deficiency and its impact on key signaling pathways.