Author

Alan Xu

University of Southern CaliforniaORCID 0000-0002-8698-9301Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Alan Xu1 paper · Johns Hopkins University

Biology Disciplines

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Genomics· 3 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:Arabidopsis· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2

Frequent Co-Authors

Bérénice Anath BenayouniD· 5 shared Bryan B. TeefyiD· 3 shared Ryan J. LuiD· 3 shared Ari AdleriD· 2 shared Katelyn HsuiD· 2 shared Minhoo KimiD· 2 shared Aaron J.J. LemusiD· 1 shared Alexandra M. TyersiD· 1 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersGenomics

Bérénice Anath BenayounORCID

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5 papers

Recent·Most cited

Estropausal gut microbiota transplant improves measures of ovarian function in adult mice

Minhoo Kim, Justin Wang, Steven E. Pilley, R. J. Lu, Alan Xu, Youngchang Kim, Minying Liu, Xueyan Fu, Sarah L. Booth, Peter J. Mullen, Bérénice Anath Benayoun

This study shows that transferring gut microbiota from young and estropausal mice improves ovarian function and fertility in adult mice.

Nature Aging · Mar 3, 2026Peer-reviewedPhysiology

Mouse peritoneal macrophages undergo female-specific remodeling with aging driven by both hormone-dependent and -independent mechanisms

Ryan J. Lu, Shiqi Chen, Minhoo Kim, Nirmal Kumar Sampathkumar, Evelyn H. Lee, Amy Christensen, Eric Wang, Isabella C. Y. Lau, Shivay Parihar, Charan K. Ravikumar, Jane Jung, Shelby Brown, Alan Xu, Julio L. Alvarenga, Kristen Mehalko, , Bérénice Anath Benayoun

This study identifies sex-specific aging-related changes in mouse peritoneal macrophages, driven by both hormone-dependent and -independent mechanisms.

bioRxiv · Jun 11, 2025 · PreprintImmunology

Transcriptional profiling of aging tissues from female and male African turquoise killifish

Alan Xu, Bryan B. Teefy, Ryan J. Lu, Séverine Nozownik, Alexandra M. Tyers, Dario Riccardo Valenzano, Bérénice Anath Benayoun

This paper provides a transcriptional dataset of aging tissues from African turquoise killifish, showing age has a greater impact than sex on gene expression and TE transcription.

Scientific Data · Oct 12, 2023Peer-reviewedGenomics

Widespread sex-dimorphism across single-cell transcriptomes of adult African turquoise killifish tissues

Bryan B. Teefy, Aaron J.J. Lemus, Ari Adler, Alan Xu, Rajyk Bhala, Katelyn Hsu, Bérénice Anath Benayoun

The paper creates a single-cell gene expression atlas of adult African turquoise killifish tissues, revealing widespread sex-dimorphic gene expression, particularly in the liver, and identifies molecular markers for sex identity.

Cell Reports · Oct 1, 2023Peer-reviewedGenomics

Dynamic regulation of gonadal transposon control across the lifespan of the naturally short-lived African turquoise killifish

Bryan B. Teefy, Ari Adler, Alan Xu, Katelyn Hsu, Param Priya Singh, Bérénice Anath Benayoun

The paper characterizes gonadal transcriptome changes across lifespan in African turquoise killifish, finding sex-specific declines in piRNA pathways and TE activity in ovaries with aging.

Genome Research · Jan 1, 2023Peer-reviewedGenomics