Author

Agathe Bernand

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Ashwin JainarayananiD· 2 shared Claire C. StatoniD· 2 shared Marcus A. WiddessiD· 2 shared Michael Loran DustiniD· 2 shared Salvatore ValituttiiD· 2 shared Amanda WickiiD· 1 shared Amandine Michelet· 1 shared Brienne McKenzieiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

Ashwin JainarayananORCID

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2 papers

Recent·Most cited

Isolation of functional supramolecular attack particles (SMAPs)

Ashwin Jainarayanan, Vineethkrishna Chandrasekar, Vinnycius Pereira Almeida, Marcus A. Widdess, Claire C. Staton, Agathe Bernand, Veronika Pfannenstill, Sarah E. Flannery, Helena Watson, Amanda Wicki, Orthi Onupom, Mirudula Elanchezhian, Jesusa Capera, Lina Chen, Salvatore Valvo, , Michael Loran Dustin

This paper develops a method to isolate and characterize SMAPs from NK-92 cells, showing their cytotoxic activity against tumor cells in vitro and in vivo.

bioRxiv · Nov 10, 2025 · PreprintImmunology

Perforin-mediated pore formation at the lytic synapse triggers the canonical pyroptotic cell death pathway

Brienne McKenzie, Marie-Pierre Puisségur, Lucie Demeersseman, Frecia Rodriguez, Emma Cini, Ashwin Jainarayanan, Marcus A. Widdess, Claire C. Staton, Lina Chen, Vincent Sibaud, Laurence Lamant, Michael Loran Dustin, Agathe Bernand, Sabina Müller, Salvatore Valitutti

This study shows perforin triggers pyroptosis in target cells by activating the NLRP3/caspase-1/gasdermin D pathway, while sustained CTL interaction leads to apoptosis.

bioRxiv · May 24, 2024 · PreprintCell Biology