Author

Shintaro Kobayashi

Hokkaido UniversityORCID 0000-0002-8735-5722Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Haruto Eguchi· 2 shared Hiroaki KariwaiD· 2 shared Hirofumi SawaiD· 2 shared Keisuke Maezono· 2 shared Koshiro TabataiD· 2 shared Michihito SasakiiD· 2 shared Passawat ThammahakiniD· 2 shared Yasuko OrbaiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersMicrobiology

Haruto Eguchi

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Interleukin-34 Promotes Activation of Disease-associated Microglia-like Cells and Attenuates Disease Progression in West Nile Virus Infection

Passawat Thammahakin, Keisuke Maezono, Thuy Thi Ngoc Duong, Haruto Eguchi, Savit Promwattanapan, Michihito Sasaki, Hiroaki Kariwa, Yasuko Orba, Shintaro Kobayashi

This study shows IL-34 promotes DAM-like microglial activation and protects against WNV infection in cell culture and mice.

bioRxiv · Aug 4, 2026 · PreprintMicrobiology

West Nile virus capsid protein promotes viral replication and pathogenesis through PKCα-dependent lamin phosphorylation and nuclear deformation

Keisuke Maezono, Passawat Thammahakin, Michiyo Kataoka, Tadaki Suzuki, Haruto Eguchi, Duong Thi Ngoc Thuy, Toshiro Yamaguchi, Akira Ota, Yukari Itakura, Koshiro Tabata, Hirofumi Sawa, Kentaro Yoshii, Hiroaki Kariwa, Shintaro Kobayashi

This paper shows that WNV capsid protein causes nuclear deformation via PKCα-dependent lamin phosphorylation, which supports viral replication and disease.

bioRxiv · Jul 23, 2026 · PreprintMicrobiology

A surrogate marker of protection confirms the efficacy of an AddaS03-adjuvanted West Nile virus subunit vaccine

Atsuko Inoue, Shinji Saito, Kaito Maeda, Yukari Itakura, Shintaro Kobayashi, Michihito Sasaki, Gabriel González, William W. Hall, Katsumi Maenaka, Yasuko Orba, Hirofumi Sawa, Koshiro Tabata

This study evaluates AddaS03 as an adjuvant for a WNV subunit vaccine, showing it elicits higher neutralizing antibody titers and provides full protection in mice compared to Alhydrogel.

bioRxiv · Apr 21, 2026 · PreprintMicrobiology