Yasuko Orba

This study shows favipiravir suppresses OROV replication and disease in hamsters, preventing neuroinvasion and pathogenic host responses through transcriptomic analysis.

This study develops a reverse genetics system for Yezo virus to investigate the role of its glycoprotein N-terminal region in replication across mammalian and tick hosts.

This study shows IL-34 promotes DAM-like microglial activation and protects against WNV infection in cell culture and mice.

This study evaluates AddaS03 as an adjuvant for a WNV subunit vaccine, showing it elicits higher neutralizing antibody titers and provides full protection in mice compared to Alhydrogel.

This paper develops a CPER-based reverse genetics system for rabies virus, enabling the generation of recombinant viruses with various genetic modifications.

This study develops a luciferase-based biosensor to detect and quantify dsRNA from various viral infections, showing broad-spectrum reactivity and utility in assessing antiviral compounds.

This study identifies and characterizes two nearly complete genomes of pigeon gammacoronaviruses, supporting their classification as a new species within the Igacovirus subgenus.

The paper identifies site-specific glycan compositions of SARS-CoV-2 spike protein using mass spectrometry and lectin microarray, revealing key glycan structures relevant to vaccine design.

LIGHTHOUSE identifies novel therapeutics for diseases including cancer, bacterial infections, and COVID-19 using a graph-based deep learning approach without requiring 3D structural data.