Author

Yukari Itakura

Hokkaido UniversityORCID 0000-0002-3463-1834Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Hirofumi SawaiD· 5 shared Koshiro TabataiD· 5 shared William W. HalliD· 4 shared Aiko Ohnuma· 3 shared Atsuko InoueiD· 3 shared Gabriel GonzáleziD· 3 shared Michihito SasakiiD· 3 shared Shinji SaitoiD· 3 shared

Activity by Year

2026-2026 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

Hirofumi SawaORCID

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5 papers

Recent·Most cited

Integrated in vivo and transcriptomic analyses of lethal Oropouche virus infection reveal suppression of pathogenic host responses by antiviral therapy

Cassia Sousa Moraes, Gabriel González, Akihiko Sato, Shigeru Miki, Atsuko Inoue, Koshiro Tabata, Joshua W. Kranrod, Chilekwa Frances Kabamba, Aiko Ohnuma, Keita Matsuno, Rio Harada, Shinji Saito, Naoki Akimoto, Michihito Sasaki, Yasuko Orba, , Yukari Itakura

This study shows favipiravir suppresses OROV replication and disease in hamsters, preventing neuroinvasion and pathogenic host responses through transcriptomic analysis.

PLoS Pathogens · Oct 7, 2026Peer-reviewedMicrobiology

West Nile virus capsid protein promotes viral replication and pathogenesis through PKCα-dependent lamin phosphorylation and nuclear deformation

Keisuke Maezono, Passawat Thammahakin, Michiyo Kataoka, Tadaki Suzuki, Haruto Eguchi, Duong Thi Ngoc Thuy, Toshiro Yamaguchi, Akira Ota, Yukari Itakura, Koshiro Tabata, Hirofumi Sawa, Kentaro Yoshii, Hiroaki Kariwa, Shintaro Kobayashi

This paper shows that WNV capsid protein causes nuclear deformation via PKCα-dependent lamin phosphorylation, which supports viral replication and disease.

bioRxiv · Jul 23, 2026 · PreprintMicrobiology

A surrogate marker of protection confirms the efficacy of an AddaS03-adjuvanted West Nile virus subunit vaccine

Atsuko Inoue, Shinji Saito, Kaito Maeda, Yukari Itakura, Shintaro Kobayashi, Michihito Sasaki, Gabriel González, William W. Hall, Katsumi Maenaka, Yasuko Orba, Hirofumi Sawa, Koshiro Tabata

This study evaluates AddaS03 as an adjuvant for a WNV subunit vaccine, showing it elicits higher neutralizing antibody titers and provides full protection in mice compared to Alhydrogel.

bioRxiv · Apr 21, 2026 · PreprintMicrobiology

Application of the CPER reverse genetics system for genetic engineering of rabies virus

Yukari Itakura, Nijiho Kawaguchi, Koshiro Tabata, Gabriel Gonzales, Kei Konishi, Aiko Ohnuma, Itsuko Furuta, Naoto Ito, Shinji Saito, William W. Hall, Yasuko Orba, Hirofumi Sawa, Michihito Sasaki

This paper develops a CPER-based reverse genetics system for rabies virus, enabling the generation of recombinant viruses with various genetic modifications.

Journal of Virology · Mar 13, 2026Peer-reviewedMicrobiology

A lethal mouse model of Oz virus infection reveals hepatic involvement and enables evaluation of antiviral and vaccine efficacy

Rio Harada, Cassia Sousa Moraes, Atsuko Inoue, Chilekwa Frances Kabamba, Koshiro Tabata, Motohito Goto, Riichi TAKAHASHI, Joshua W. Kranrod, Shūichi Ōsawa, Aiko Ohnuma, Saito Shinji, Gabriel González, Noriko Nagata, Mamoru Ito, Makoto Suematsu, , Yukari Itakura

This study establishes a lethal mouse model of Oz virus infection, revealing hepatic involvement and demonstrating the efficacy of antiviral drugs and vaccines against the virus.

bioRxiv · Jan 29, 2026 · PreprintMicrobiology