Kiyoshi Naruse

The paper generates a multi-tissue RNA-seq atlas of adult medaka under salinity and seasonal contrasts to study gene-expression plasticity and comparative biology.

The study shows that external nutrient inputs have limited impact on phytoplankton growth in Mikawa Bay due to iron-driven internal phosphorus cycling, highlighting the need for integrated management strategies.

This study shows oxytocin signaling is essential for maturing TN-GnRH3 circuits and regulating mate preference in medaka, with C1q-dependent synaptic mechanisms involved.

The paper shows that prolonged stemness in the tail of Japanese eels drives extreme axis segmentation through delayed Hox13 activation and sustained Oct4 expression.

MedakaBase provides a centralized platform for genomic resources and analysis tools for medaka fish, including gene models and omics data for multiple Oryzias species.

The paper analyzes the relationship between nutrient concentrations and phytoplankton growth in Ise Bay and Mikawa Bay to determine optimal nutrient levels for healthy ecosystems.

The paper maps and validates key genetic loci influencing heart rate and function in fish, identifying potential targets for cardiac disease treatment.

The paper uses medaka fish to study genetic and environmental interactions in heart rate, identifying QTLs and validating genes, while showing limitations of GWAS in capturing complex genetic effects.

This study identifies phod1 as a gene regulating seasonal energy metabolism via the growth hormone pathway in Japanese medaka fish.

This study shows that spatial and temporal control of axis segmentation in medaka fish are dissociable modules, identified through devQTL mapping and CRISPR validation.

This study shows that Pax3 and Pax7 work with Mitf to control melanophore and xanthophore development in medaka and zebrafish, revealing a conserved but complex regulatory network.

The paper introduces the Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel, a vertebrate genetic resource for genotype-to-phenotype studies, enabling controlled experiments on complex traits.

The paper analyzes genomic and epigenomic variation in the MIKK panel using long-read sequencing and pan-genome graphs, revealing novel structural variants and methylation patterns.

This paper identifies a medaka mutant with congenital intestinal atresia, linking Mypt1 dysfunction to actomyosin dysregulation and epithelial disorganisation.

The paper presents a high-quality draft genome assembly of Oryzias javanicus, focusing on its adaptation to salinity.

The paper identifies kit-ligand a as the gene responsible for the medaka pigment cell mutant few melanophore and shows its role in pigment cell specification.

The paper identifies distinct homeostatic and growth adult stem cell populations in medaka gills, showing their spatial separation and functional specialization.