Author

Young J. Yoon

Albert Einstein College of MedicineORCID 0000-0002-8772-9624Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:protein design· 1

Frequent Co-Authors

Pablo E. CastilloiD· 3 shared Robert H. SingeriD· 2 shared Shivani C. KharodiD· 2 shared Dong-Woo HwangiD· 1 shared Hannah R. MondayiD· 1 shared Heejun ChoiiD· 1 shared Kaoutsar NasrallahiD· 1 shared Kyle J. Yoon· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Pablo E. CastilloORCID

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3 papers

Recent·Most cited

Phosphorylation alters FMRP granules and determines their transport or protein synthesis abilities

Shivani C. Kharod, Dong-Woo Hwang, Heejun Choi, Kyle J. Yoon, Pablo E. Castillo, Robert H. Singer, Young J. Yoon

This study shows that phosphorylation of FMRP at S499 alters granule structure and function, affecting transport and translation in neurons.

bioRxiv · Mar 15, 2023 · PreprintNeuroscience

Activity-dependent LTP in the dentate gyrus promotes epileptic seizures

Kaoutsar Nasrallah, M. Agustina Frechou, Young J. Yoon, Subrina Persaud, Tiago Gonçalves, Pablo E. Castillo

The paper shows that initial seizures in mice increase mossy cell-granule cell synaptic transmission via BDNF-dependent LTP, which worsens seizures and suggests a mechanism for epileptogenesis.

bioRxiv · Jun 30, 2021 · PreprintNeuroscience

Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals

Hannah R. Monday, Shivani C. Kharod, Young J. Yoon, Robert H. Singer, Pablo E. Castillo

This study shows that presynaptic FMRP and local protein synthesis regulate structural and functional plasticity in hippocampal mossy fiber-CA3 synapses.

Neuron · Jan 1, 2021Peer-reviewedNeuroscience