Daniel A. Notterman

Epigenetic and brain age across development: Performance and associations in the MIND consortium

Across 15 cohorts (birth to 24 years), 20 epigenetic clocks and eight brain age models predicted chronological age modestly, stabilizing by middle childhood; their age residuals were weakly associated.

Modeling Sex Differences and Neurodegeneration in Repetitive Traumatic Brain Injury Using Drosophila

This paper develops a Drosophila model of repetitive traumatic brain injury to study sex-specific behavioral, proteomic, and neurodegenerative outcomes.

Differential Methylation by Early Life Adversity in the Future of Families Child Wellbeing Study

The paper examines DNA methylation changes linked to early life adversity in the FFCWS cohort, finding specific, functional genomic regions associated with mental health disorders.

Social isolation upregulates takeout expression in female Drosophila melanogaster to promote sucrose feeding

This study shows social isolation upregulates takeout in female Drosophila, increasing sucrose feeding, while having opposite effects in males.

Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections

This study uses proteomics to analyze immune responses in tracheal aspirate and plasma from critically ill children with viral lower respiratory tract infections, identifying diagnostic biomarkers and correlations with viral load and coinfections.

Measuring the long arm of childhood in real-time: Epigenetic predictors of BMI and social determinants of health across childhood and adolescence

This study shows that epigenetic-BMI measured from children's saliva is a valid biomarker of BMI and reflects social inequalities in childhood and adolescence.

Differentially methylated regions and methylation QTLs for teen depression and early puberty in the Fragile Families Child Wellbeing Study

The paper identifies differentially methylated regions and methylation QTLs associated with teen depression and early puberty using longitudinal DNA methylation data from the Fragile Families Child Wellbeing Study.