Vera D. Rinaldi

This study creates a single-cell RNA-seq atlas of the mouse seminal vesicle, identifying secretory and immune cell populations and their transcriptomes.

The paper identifies post-transcriptional regulators in early human small intestinal development using multi-omic analyses and presents a web tool for exploring miRNA regulation.

The paper shows that Cre recombinase can be transported from somatic tissues to the male reproductive tract in mice, suggesting inter-tissue RNA or protein trafficking.

This study shows that Rlim is essential for spermiogenesis in male mice, as its deletion leads to defective sperm production and fertility issues.

This study identifies miR-375 as a key regulator of intestinal crypt homeostasis, showing its role in stem cell proliferation, tuft cell abundance, and resistance to infection and cancer.

The paper creates a single-cell atlas of the murine epididymis and vas deferens, identifying cell types and their regional specialization, and revealing potential signaling networks.

The paper examines cytosine methylation changes in sperm during post-testicular maturation and finds minimal changes, with an unexpected extracellular DNA contamination in caput epididymal sperm.

The paper shows that CHK1/CHK2 signaling to TRP53/TAp63 eliminates oocytes with unrepaired meiotic DSBs or asynaptic chromosomes.

The paper shows that the CHK2-dependent checkpoint eliminates mouse oocytes with DNA damage or synapsis failure by detecting and removing those with unrepaired DSBs or unsynapsed chromosomes.

This study shows that MCMDC2 is essential for meiotic DNA break repair and homolog pairing in mice, with phenotypes similar to MSH4/5 deficiency.