Chao Yun Irene Yan

The paper constructs and compares PPI networks of drug targets in nociceptor subtypes across mouse and human DRGs, revealing species-specific conservation and broader cellular roles of key drug targets.

The paper investigates how maternal pro-inflammatory responses affect Cdh1/E-cadherin epigenetic regulation and craniofacial development in embryos.

This study investigates how the lens placode modulates extracellular matrix formation during early eye development in chicken and mouse models, showing a role for BMP signaling and Timp2 in ECM remodeling.

The paper shows that Ash1 repressor binds to the HO promoter in yeast, requiring nucleosome eviction by Swi5 for access, and that this process is linked to repression and promoter resetting.

The paper shows that the Mediator Tail module can be recruited independently to the HO promoter in yeast, suggesting the core Mediator complex limits coactivator recruitment and gene activation.

This study investigates the functional roles of SNAG, SCRATCH, and newly identified HINGE domains in chicken Scratch2, revealing their contributions to transcriptional repression and nuclear localization.