T cell-microbiome associations captured through T cell receptor convergence analysis
Romi Vandoren, My Kieu Ha, Vincent M.L. Van Deuren, Naomi De Roeck, Ting Pu, Eelco Christiaan Brand, Maria S. Kuznetsova, Hajar Besbassi, Esther Bartholomeus, Fabio Affaticati, Ilke De Boeck, Thies Gehrmann, Sarah Lebeer, Bas Oldenburg, Femke van Wijk, , Pieter Meysman
The paper introduces AIRRWAS, a framework to identify T cell receptor convergence with bacterial genera, revealing reproducible associations across cohorts and functional T cell responses.
bioRxiv · Sep 30, 2025 · PreprintBioinformatics