Author

Zhiying Wu

Chinese Academy of Medical Sciences & Peking Union Medical College

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Bin SheniD· 1 shared Chong Chang· 1 shared Chonghao CheniD· 1 shared Chu‐Xia DengiD· 1 shared Enni Zhu· 1 shared Fubin LiiD· 1 shared Geng Li· 1 shared Haiyan ZhangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Bin ShenORCID

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2 papers

Recent·Most cited

Elimination of intramuscular immunoglobulin accumulation alleviates Duchenne Muscular Dystrophy

Li Zhang, Wenting Guo, Mei Huang, Z Y Liang, Enni Zhu, Geng Li, Chong Chang, X S Guo, Wenjie Sun, Jia Li, J S Liu, Han Qiu, L C Zhu, Shuaiwei Ren, Raoxian Bai, , Xing Chang

This study identifies IgG accumulation in dystrophin-deficient muscle as a driver of DMD progression and shows that B cell depletion reduces it, offering a potential therapeutic strategy.

bioRxiv · Feb 12, 2026 · PreprintImmunology

YTHDF2 upregulation and relocation dictate CD8 T cell polyfunctionality in tumor immunity

Haiyan Zhang, Xiao-Jing Luo, Wei Yang, Zhiying Wu, Zhicong Zhao, Xin Pei, Xue Zhang, Chonghao Chen, Josh Haipeng Lei, Qingxia Shi, Qi Zhao, Yanxing Chen, Wenwei Wu, Zhao-Lei Zeng, Huai‐Qiang Ju, , Jiajie Hou

This paper shows YTHDF2 upregulation and nuclear relocation enhance CD8 T cell polyfunctionality and tumor immunity by regulating gene transcription and mitochondrial fitness.

Nature Communications · Nov 5, 2024Peer-reviewedImmunology