Arjune Sen

Transcription factor binding and individual genetic risk for valproate teratogenicity

The paper investigates how genetic variants affecting transcription factor binding contribute to valproate-induced birth defects and identifies EP300 as a key regulator involved in this process.

Effects of focal epilepsy and aging on discrimination and reactivation of memories

This study introduces a behavioral task to measure pattern separation and completion, showing deficits in pattern completion in focal epilepsy and degraded pattern separation in aging.

Active cortical networks promote shunting fast synaptic inhibition in vivo

The paper investigates GABAAR signaling in awake versus anesthetized mouse cortex, finding that awake networks exhibit shunting inhibition due to depolarized GABAAR equilibrium potentials.

Optogenetic determination of dynamic and cell-type-specific chloride equilibrium potentials

The paper uses an optogenetic approach to measure dynamic and cell-type-specific chloride equilibrium potentials in rodent neurons.